Correlation Analysis of Drug Resistance and Resistant Genotypes of Pathogenic Klebsiella peneumoniae from Racoon Dog to Fluoroquinolones

• 作者: Bai Xue Feng Ling Fu Yanfang Gao Qingshan Jia Qinghui Liu Zhiqiang Luo Junfeng Shi Qiumei Wu Tonglei Yao Weiping Zhang Zhiqiang Zhao Xiaocui
• 来源期刊: 动物与饲料科学:英文版
• 学科: 农学
• 关键词: Racoon DOG KLEBSIELLA peneumoniae DRUG sensitivity test DRUG resistance DRUG-RESISTANT genotype
• 年，卷（期）: 2019,（1）
• 页码范围: 35-38
• 页数: 4页
• 分类号: S

摘要

[Objective] The paper was to analyze the correlation between drug resistance and resistant genotypes of pathogenic Klebsiella peneumoniae from racoon dog to fluoroquinolones.[Method] The drug resistance and resistant genes of 24 strains of pathogenic K. peneumoniae from racoon dog to fluoroquinolones were detected by K-B drug susceptibility paper and PCR.[Result] Multiple drug-resistant strains were dominant among 24 strains of pathogenic K. peneumoniae, and the drug resistance to levofloxacin, enrofloxacin, ciprofloxacin and norfloxacin was 70.8%-79.2%;the strains resistant to 4, 3 and 2 antibiotics were 58.3%, 29.2% and 8.3%, respectively. The detection rates of drug-resistant genes TEM, gyrB, parC,parE, gyrA and SHV were 75%-100%, and the number of strains carrying 9, 8, 7, 6, 4 and 3 drug-resistant genes was 4.2%-41.7%. Comparison of drug-resistant genes and drug resistance showed that the coincidence rates of levofloxacin, enrofloxacin, ciprofloxacin and norfloxacin were 78.9%-100%.[Conclusion] There were certain correlation between drug resistance and resistant genotypes of 24 strains of pathogenic Klebsiella peneumo-niae to fluoroquinolones.