Multiple Marker Effects of Single Nucleotide Polymorphisms in Two Genes, <i>NCAPG</i>and <i>PLAG1</i>, for Carcass Weight in Japanese Black Cattle

• 作者: Youji Muramatsu
• 来源期刊: 动物科学期刊(英文)
• 学科: 医学
• 关键词: Association BEEF CATTLE CARCASS Weight Interaction SNP
• 年，卷（期）: 2019,（1）
• 页码范围: 129-134
• 页数: 6页
• 分类号: R73

摘要

Carcass weight is an economically important trait for beef cattle breeding and markets. The previous studies detected two single nucleotide polymorphisms (SNPs) associated with carcass weight of Japanese Black: c.1326T>G in NCAPG gene and FJX_250879 in PLAG1 gene. Here, I carried out multiple marker association analysis for the two SNPs in Japanese Black population of 218 animals. The multiple marker analysis with the model including the main effects of the two SNPs and their interaction detected significant main effects of c.1326T>G and FJX_250879 and a significant interaction between the two SNPs, for carcass weight. These findings suggest the presence of inter-allelic interactions among genes affecting the variation of carcass weight. For effective marker-assisted selection for beef production, interaction between the two markers needs to be considered.