Research trends and development status of TCM network pharmacology: a bibliometric study

• 作者: Gang Fang Qing-Huai Zhang Qiu-Xia Chen Xiu-Song Tang Yu-Zhi Shang Yu-Zhou Pang
• 来源期刊: 药物联合治疗
• 学科: 医学
• 关键词: Chinese materia MEDICA NETWORK PHARMACOLOGY BIBLIOMETRIC analysis CITESPACE VOSviewer
• 年，卷（期）: 2019,（3）
• 页码范围: 102-116
• 页数: 15页
• 分类号: R

摘要

Objective: To analyze the research status, development context and trend of traditional Chinese medicine (TCM) network pharmacology from birth to the present. Methods: In this study, bibliographic data and references of articles on TCM network pharmacology were collected from Web of Science Core Collection (WoSCC), and software including CiteSpace, VOSviewer and Microsoft Excel were applied for the bibliometric analysis of periodicals and the quantity of literature, and for the construction and analysis of the co-occurrence network of countries, journals, research institutes and authors, clusters of co-cited references, and time distribution network of keywords. Results: 249 articles were included in this study. The time span was from 2011 to 2018, and the annual volume of publications showed an increasing trend year by year. The 77 journals contain relevant literature, and the average impact factor of the journal is 3.215. Chinese Journal of Natural Medicines, Scientific Reports, PLoS One have high influence in the field of TCM network pharmacology. Universities and research institutes including China Academy of Chinese Medical Science and Northwest Agriculture & Forestry University are the major forces in this field. Wang Yonghua and Li Shao are authors with high influence in this field, with a considerable number of relevant documents and citations. According to the clustering results of co-cited references, research topics can be classified into 13 development contexts such as “compound danshen formula”,“computational tool”, and “new multi-compound drug discovery”. Hotspots of TCM network pharmacology include “drug discovery”,“mechanism” and “cardiovascular disease”, and relevant research methods and research contents including drugs and diseases tend to be constantly enriched. Conclusion: This study comprehensively demonstrates the research status, development context and trends of TCM network pharmacology, and provides a scientific reference for TCM network pharmacology researchers.