Materials and Methods:This was a retrospective review of all patients seen at Pathology Department,Hue Central Hospital with the diagnosis of nasopharyngeal carcinoma between January 1,2017 and June 30,2018.The patient’s clinical data and histopathological findings are presented.The histopathological diagnosis was in accordance with the World Health Organization(WHO)1991 classification table.Results:A total of 73 patients with histologically confirmed nasopharyngeal carcinoma were recorded at Hue Central Hospital.There were 53 males and 20 females.Histologically,undifferentiated carcinoma was the commonest(71.2%)followed by well-differentiated keratinizing squamous cell carcinoma(20.6%)and other carcinoma(8.2%).Immunohistochemistry with CKAE1/3 was positive to 32/32 of well-differentiated keratinizing squamous cell carcinoma,and negative to 30/32 of undifferentiated carcinoma.