Free autologous internal limiting membrane transplantation in the treatment of large macular hole

• 作者: Fei-Yan Ma Peng-Fei Chen Rui-Jie Xi Yu-Hua Hao
• 来源期刊: 国际眼科杂志:英文版
• 学科: 医学
• 关键词: vitreoretinal disease MACULAR HOLE internal LIMITING membrane VITRECTOMY
• 年，卷（期）: gjykzzywb_2019,（5）
• 页码范围: 848-851
• 页数: 4页
• 分类号: R779.6

摘要

We evaluated the clinical efficacy of free internal limiting membrane(ILM) flap transplantation for the treatment of large macular hole over 500 μm in 42 consecutive patients. Quantified evaluation of the post-operative macular anatomy restoration was performed by spectral-domain optical coherence tomography in the 12 mo follow-up. The results showed 41 eyes achieved successful closure(97.6%). Postoperative best corrected visual acuity, ellipsoid layer, and external limiting membrane disruption were significantly improved at all follow-up time points. The central foveal thickness was significantly higher at 1 mo. We concluded that free ILM flap transplantation proves to be effective to achieve anatomical and functional improvement for the treatment of large macular hole.