Renal function and choroidal thickness using swept-source optical coherence tomography in diabetic patients

• 作者: Antonio Manuel Garrido-Hermosilla Cristóbal Morales-Portillo Eduardo Esteban-González Enrique Rodríguez-de-la-Rúa-Franch Estanislao Gutiérrez-Sánchez Isabel Relimpio-López María Asunción Martínez-Brocca María Jesús Díaz-GrANDa Mariola Méndez-Muros
• 来源期刊: 国际眼科杂志:英文版
• 学科: 医学
• 关键词: choroidal thickness renal function swept-source OPTICAL COHERENCE TOMOGRAPHY SPECTRAL-DOMAIN OPTICAL COHERENCE TOMOGRAPHY diabetes MELLITUS
• 年，卷（期）: 2019,（6）
• 页码范围: 985-989
• 页数: 5页
• 分类号: R587.2

摘要

AIM: To assess the relationship between choroidal thickness and renal function in diabetic patients. METHODS: Cross-sectional retrospective clinical study of 42 eyes of 21 ocular treatment-na?ve diabetic patients. Demographic data included: age, sex, type and course of diabetes. Ocular data included: severity of diabetic retinopathy;retinal thickness at the central macular region, as well as choroidal thickness at the central and paracentral quadrants, using automatically generated maps by swept-source optical coherence tomography;presence of cystic macular edema;and ocular axial length(AXL). Lab-test parameters included: glycated hemoglobin(HbA1c), albuminuria, albumin/creatinine ratio in urine, and glomerular filtration rate. RESULTS: A significant negative correlation was mainly observed between several choroidal thicknesses, age(P<0.020) and ocular AXL(P<0.030). On the contrary, a significant positive correlation was found between all choroidal thicknesses, HbA1 c(P<0.035) and albuminuria(P<0.040). CONCLUSION: Choroidal thickness can represent an additional tool to help clinicians predicting the renal status in ocular treatment-na?ve diabetic patients.