Retinal nerve fiber and ganglion cell layer thinning in hereditary and acquired mitochondrial optic neuropathies

• 作者: Josef Finsterer
• 来源期刊: 国际眼科杂志:英文版
• 学科: 医学
• 关键词: RETINAL nerve fiber and ganglion cell layer THINNING in HEREDITARY and ACQUIRED mitochondrial OPTIC NEUROPATHIES
• 年，卷（期）: 2019,（10）
• 页码范围: 1666-1666
• 页数: 1页
• 分类号: R774.6

摘要

Dear Editor,With interest we read the article by Teng et al[1]about a study of the retinal nerve and ganglion cell layers by means of optic coherence tomography(OCT)in 32 patients with a mitochondrial optic neuropathy(MON).Included were 20 patients with hereditary MON[Leber’s hereditary optic neuropathy(LHON)],12 patients with acquired MON[ethambutol-induced optic neuropathy(EION)],and 41 healthy controls.Retinal nerve fiber layer(RNFL)thickness was reduced in the nasal,superior,temporal,and inferior quadrants in LHON patients but only in the temporal quadrant in the EION patients.Thickness of the retinal ganglion cell layer(RGCL)was similarly reduced in LHON and EION patients.We have the following comments and concerns.