A New Supplement for the Treatment of Metabolic Syndrome in Postmenopausal Women

• 作者: Alessandra Bitto Annamaria Giacobbe Roberta Granese Rosario D’Anna Vincenzo Arcoraci
• 来源期刊: 食品与营养科学(英文)
• 学科: 医学
• 关键词: METABOLIC Syndrome POSTMENOPAUSE Insulin Resistance CINNAMON Corosolic ACID Glycyrrhizic ACID
• 年，卷（期）: 2020,（1）
• 页码范围: 23-31
• 页数: 9页
• 分类号: R58

摘要

Background: Metabolic Syndrome (MS) is considered a cluster of metabolic abnormalities whose pathogenesis is principally attributable to insulin resistance. Lack of estrogens occurs in postmenopausal women and worsening insulin resistance and lipid profile, predispose to MS. The aim of the study was to show whether a new supplement containing cinnamon, corosolic acid and glycyrrhizic acid may counteract MS manifestations. Methods: A total of 60 postmenopausal women were enrolled in a randomized, controlled trial;the active treatment group was taking the new supplement for 3 months and was on a hypocaloric diet, control group was only on diet. At the beginning and after 3 months, metabolic variables were evaluated. Results: After 3 months, a significant difference in the treated group was observed for glucose, HOMA, total cholesterol and HDL-cholesterol;whereas, in the control group, a significant difference was shown only for glucose. After 3 months, a significant difference between groups was highlighted only for HDL-cholesterol. Conclusion: This study has shown the naturally occurring components of this new supplement may improve insulin resistance and lipid profile in a small sample of postmenopausal women.