Phytochemical Screening and Antimicrobial Activity of <i>Desmodium ramosissimum</i>

• 作者: Adjanohoun Adolphe Assogba Sylvestre Baba-Moussa Lamine Badé Farid Toyigbénan Dah-Nouvlessounon Durand Halfane Lehmane Moussè Wassiyath Nabéde Aklesso Nanoukon Chimène Nounagnon Martial Savadogo Aly Sina Haziz Tohoyéssou Majoie
• 来源期刊: 美国植物学期刊(英文)
• 学科: 医学
• 关键词: DESMODIUM BENIN EXTRACTS ANTIMICROBIAL Screening
• 年，卷（期）: 2020,（1）
• 页码范围: 51-63
• 页数: 13页
• 分类号: R28

摘要

Microbial infections threaten the health of the Beninese population. Objectives: To identify bioactive phytochemical groups and evaluate the antimicrobial activity of Desmodium ramosissimum used in traditional medicine in Benin against microbial infections. Methodology & Results: The classic reactions in solution helped highlight alkaloids, anthocyanins, flavonoids, quinones, saponins, steroids, tannins, terpenoids, mucilage, Coumarin, reducing compounds, anthracene, glycosides. The antibacterial activity was evaluated by extracts dilution’s method (ethanol extracts, methanol extracts and hexane extracts). The methanol extract inhibited the growth of all tested germs, with a significant effect on E. coli and S. aureus strains whose MIC values are equal to 1.25 mg/ml. On the contrary, this extract has a low activity on P. vulgaris strain with a MIC of 10 mg/ml. The ethanol extract also inhibited the growth of all the tested strains, but with more intense activity than the methanol extract. The strains of C. albicans and S. oralis were more sensitive to the extract with 0.625 mg/ml for MIC, while S. aureus and P. vulgaris were less sensitive (MIC = 5 mg/ml). The residual ethanol extract exerted inhibition on all microorganisms at a concentration of 20 mg/ml, except the strain of E. foecalis that was resistant. Conclusion & Applications: This study shows that besides its food virtues of this plant, there are antibacterial and antifungal properties.