The First Case of Human Herpesvirus 7-Related Epilepsy in the Republic of Belarus

• 作者: Elena Kishkurno Igor Zaitsau Katerina Divakova Oxana Romanova Svetlana Belaya Tamara Amvrosieva Yuliya Shilova
• 来源期刊: 药剂与药理学:英文版
• 学科: 医学
• 关键词: HHV-7 EPILEPSY CHILD CASE REPORT treatment
• 年，卷（期）: 2020,（3）
• 页码范围: 73-76
• 页数: 4页
• 分类号: R37

摘要

Background:Human herpesvirus(HHV)-7 is usually associated with febrile seizures.Later onset and higher frequency of seizures are characteristic of pediatric HHV-7,compared with HHV-6 infection.The HHV-7-related severe neurological disorders are predominantly observed in immunocompromised individuals.Reports of healthy individuals with HHV-7 infection and diverse neurological disorders are limited.Patient Description:We present a case of HHV-7-related epilepsy in an immunocompetent 11-year old boy and extensive infectious and autoimmune testing positive only for HHV-7 in the cerebrospinal fluid.The patient made a good recovery after treatment with intravenous immunoglobulin and methylprednisolone.Discussion:This is the first reported case of epilepsy associated with HHV-7 in a previously healthy individual.It also demonstrates that intravenous immunoglobulin and steroids may be used in the course of this disorder and may be beneficial for recovery.