Antibacterial Activities of the Ethanolic Extract of <i>Crateva adansonii</i>DC. (Capparidaceae) Harvested in Dassa-Zoumèin Central Bénin

• 作者: Armel Géraldo Houndeton Armelle Sabine Yélignan Hounkpatin Eustache Enock Houéto Gratien Boni Madjid Olatoundé Amoussa Roch Christian Johnson Wilfrid Hinnoutondji Kpètèhoto Zinsou Franck Mignanwandé
• 来源期刊: 医学微生物学(英文)
• 学科: 医学
• 关键词: Antibacterial Activity Crateva adansonii Ethanolic Extract BENIN
• 年，卷（期）: 2020,（2）
• 页码范围: 46-57
• 页数: 12页
• 分类号: R28

摘要

<strong>Objective: </strong>The present was initiated to study the antibacterial properties of the <i>Crateva adansonii</i> DC extract on germs commonly identified in skin and digestive infections in Benin as well as the reversion of resistance to these aforementioned germs. <strong>Method: </strong>The bacteria’s sensitivity test to extracts was carried out by the microdilution method in liquid medium as well as the MIC and the reversion of bacterial resistance. For the determination of the MBC, this technique is used coupled with spreading on agar medium. <strong>Results: </strong>The results show an antibacterial activity of the extract with MICs between 0.625 - 5 mg/ml. The CMB of <i>Enterococcus faecalis</i> ATCC 29212 is 2.5 mg/ml while that of Methicillin-resistant <i>Staphylococcus aureus</i> and <i>Staphylococcus epidermidis</i> CIP 8039 is 5 mg/ml. The reversion of bacterial resistance has shown a synergy of action between our extract and conventional antibiotics.