Amide Synthesis through Selective Partial Hydrolysis of Nitriles in Alkaline Media

• 作者: Elvira Santos-Santos Eva F.Lejarazo-Gómez Raymundo Yáñez-Alarid
• 来源期刊: 化学与化工:英文版
• 学科: 化学
• 关键词: Amide hydrolysis of nitriles.
• 年，卷（期）: 2020,（2）
• 页码范围: 53-65
• 页数: 13页
• 分类号: O62

摘要

Amides were obtained through partial hydrolysis of nitriles,using two different energy sources,traditional heating with solvent reflux and ultrasound.The reaction was performed at micro and semi-micro scales and at different reaction time with both energy sources.Yield was determined through gas chromatography,in the case of micro-scale and weight loss in the case of semi-micro scale.