Comparison between Visualization of Microcalcifications by Digital Breast Tomosynthesis and Full-Field Digital Mammography

• 作者: Hitomi Tani Izumi Miki Nachiko Uchiyama Ryusuke Murakami Shinichiro Kumita Tamiko Yoshida
• 来源期刊: 放射学期刊(英文)
• 学科: 医学
• 关键词: BREAST Breast Cancer MICROCALCIFICATIONS Digital Mammography Digital Breast Tomosynthesis
• 年，卷（期）: fsxqkyw,（2）
• 页码范围: 90-100
• 页数: 11页
• 分类号: R73

摘要

<strong>Objective:</strong> To date, few studies have compared the diagnostic performance and visibility of microcalcifications obtained using digital breast tomosynthesis (DBT) with those obtained from full-field digital mammography (FFDM). The visualization and characterization of microcalcifications with DBT remain controversial. The purpose of this study was to compare the visibility of microcalcifications and determine whether DBT exhibits a diagnostic advantage for visualizing microcalcifications over FFDM.<strong> Methods: </strong>We retrospectively reviewed 120 cases including DBT and FFDM imaging (60 histologically verified as breast cancers and 60 as benign microcalcifications or normal). DBT images with a wide scan-angle of 50<span style="white-space:nowrap;"><span style="white-space:nowrap;">&deg;</span></span> and FFDM images were obtained using a flat-panel system (MAMMOMAT Inspiration, Siemens). Images were independently reviewed by four board-certified radiologists and evaluated for the presence of microcalcifications, probability of malignancy (BI-RADS classification), and visibility. <strong>Results:</strong> In predicting the malignancy of detected microcalcifications, no significant difference was found between readers’ areas under the receiver operating characteristic curve for DBT and FFDM (p = 0.068). The visibility scores of detected microcalcifications were 3.74 <span style="white-space:nowrap;"><span style="white-space:nowrap;"><span style="white-space:nowrap;">&plusmn;</span></span></span> 1.06 for DBT and 3.46 <span style="white-space:nowrap;"><span style="white-space:nowrap;"><span style="white-space:nowrap;">&plusmn;</span></span></span> 0.93 for FFDM, respectively. The visibility of microcalcifications when using DBT was found to be significantly superior to that of FFDM (p < 0.05). <strong>Conclusion:</strong> Our results suggest that the image quality of DBT with a wide scan-angle is comparable or superior to that obtained with FFDM in terms of both visibility and assessment of