<i>Bacillus cereus</i>Group Exhibits More Resistant to Chlorhexidine Rather Than <i>Bacillus subtilis</i>Group

• 作者: Akira Okamoto Ikumi Inoue Juntaro Kato Kokoro Tasaka Miho Kamako Saki Otsuji
• 来源期刊: 医学微生物学(英文)
• 学科: 数学
• 关键词: Bacillus cereus Bacillus subtilis Chlorhexidine Susceptibility
• 年，卷（期）: 2020,（3）
• 页码范围: 139-152
• 页数: 14页
• 分类号: O17

摘要

<span "="" style="line-height:1.5;"><span style="font-family:Verdana;">Chlorhexidine is a widely used antiseptic agent;however, its bactericidal effect against bacterial endospores is limited. The genus </span><i><span style="font-family:Verdana;">Bacillus</span></i><span style="font-family:Verdana;"> is spore-</span></span><span "="" style="line-height:1.5;"><span style="font-family:Verdana;">forming gram-positive bacteria that are ubiquitously found in the environment and cause opportunistic infection and food poisoning. The susceptibility of bacterial endospores to chlorhexidine was previously evaluated in </span><i><span style="font-family:Verdana;">Bacillus</span></i> <i><span style="font-family:Verdana;">subtilis</span></i><span style="font-family:Verdana;">, but the primary target for disinfection with antiseptic agents, including chlorhexidine, should be harmful strains. We aimed to evaluate the susceptibility of harmful </span><i><span style="font-family:Verdana;">cereus</span></i><span style="font-family:Verdana;"> group including </span><i><span style="font-family:Verdana;">Bacillus</span></i> <i><span style="font-family:Verdana;">cereus</span></i><span style="font-family:Verdana;">, and to compare that with harmless </span><i><span style="font-family:Verdana;">Bacillus</span></i><span style="font-family:Verdana;"> species, containing </span><i><span style="font-family:Verdana;">B.</span></i> <i><span style="font-family:Verdana;">subtilis</span></i><span style="font-family:Verdana;">. We evaluated the susceptibility of the 15 strains of the </span><i><span style="font-family:Verdana;">cereus</span></i><span style="font-family:Verdana;"> group to chlorhexidine in comparison with the 5 other strains, named the </span><i><span style="font-family:Verdana;">subtilis</span></i><span style="font-family:Verdana;"> group in this study. Our results indicated that chlorhexidine exerted a bacteriostatic effect against </span><i><span style="font-family:Verdana;">Bacillus</span></i><span style="font-family:Verdana;