Genetic Advances in Genome and Phenotypic Characters of Domestic Dog

• 作者: Chen Chao Deng Weidong Li Jing Li Liguang Wan Jiusheng Xiong Heli Yue Rui
• 来源期刊: 动物与饲料科学:英文版
• 学科: 医学
• 关键词: Domestic dog Genetic evolution GENOME Linkage disequilibrium Phenotypic trait genes
• 年，卷（期）: 2020,（2）
• 页码范围: 15-22
• 页数: 8页
• 分类号: R73

摘要

Dogs represent such a rich potential resource to further understand diseases and genetic traits.Comparing the genomes of three species of canine,human,and rat in terms of genome analysis,it is found that dogs are highly conservative with humans and rats.The special population structure of dogs makes it a good model for studying the diversity of morphology and behavior,the genetic basis of mammalian evolution,and dis-eases.This article gives a brief review of recent advances in domestic dog origin and evolution,genomic structure,genetic variation in dog pheno-typic characteristics,and gene mapping.These research results are expected to provide a better theoretical basis for canine genetic breeding re-search and provide new ideas and methods for the prevention,diagnosis and treatment of human diseases.