CT Imaging Evolution of Novel Coronavirus Pneumonia during Hospitalization

• 作者: Youmin Guo^‡
• 来源期刊: 放射学期刊(英文)
• 学科: 医学
• 关键词: Novel Coronavirus Pneumonia (COVID-19) CT Features Follow-Up Studies
• 年，卷（期）: 2020,（3）
• 页码范围: 127-137
• 页数: 11页
• 分类号: R73

摘要

<strong>Object:</strong> To evaluate CT Features on serial thin-section computed tomographic (CT) scans in patients with conventional Novel Coronavirus Pneumonia (COVID-19) for the period during which they remained hospitalized. <strong>Methods:</strong> In this Retrospective study, we collected clinical information including Laboratory investigations and more importantly we focused on collecting imaging data of these 15 selected patients (8 men and 7 women, 22 - 70 years old, average age (45 <span style="white-space:nowrap;">±</span> 15)) with COVID-19 disease. The mean time between the initial and repeat thin-section CT scans was 3.3 <span style="white-space:nowrap;">±</span> 2.1 days, 7.9 <span style="white-space:nowrap;">±</span> 2.1 days, 14.2 <span style="white-space:nowrap;">±</span> 1.3 days after onset of symptoms in these 15 patients. Three experienced Radiologists reviewed the CT images independently and also in collaboration with each other for complicated or unique cases, for the Imaging characteristics like number and site of lesions, distribution of lesions whether it is lobular, lobar, unilateral or bilateral, and comparing the severity of disease in relation to the CT findings. The CT features were compared using the χ² test and <em>Fisher’s </em>exact probability.<strong> Results:</strong> All of 15 patients had a history of visit to the endemic center <em>i.e.</em> Wuhan city or came in direct contact with an infected individual. Fever (93.3%) was the most common symptom. Majority of patients had a normal white blood cell count, and normal lymphocyte count although there were patients with leucopenia and lymphocytopenia. CT images showed predominate Ground-Glass opacities in the initial and repeat CT scans with a percentage of 90.6%, 53.9%, 44.2% respectively during the three spaced CT examinations;most patients had bilateral lung involvement (60%, 93.3%, 93.3%), the lesions predominantly involved the posterior (87.5%, 71.9%, 76.6%) and peripheral (90.6%, 84.3%, 85.7%) part of