Repeat OGTT at 34 - 36 Weeks to Detect the Late Occurrence of GDM: A Descriptive Cross-Sectional Study Conducted at the Professorial Unit, Teaching Hospital Peradeniya, Sri Lanka

• 作者: Chaminda Kandauda W. M. M. P. B. Wanasinghe
• 来源期刊: 生殖科学(英文)
• 学科: 医学
• 关键词: Gestational Diabetes Oral Glucose Tolerance Test Sri Lanka Maternal and Perinatal Morbidity
• 年，卷（期）: 2020,（3）
• 页码范围: 157-165
• 页数: 9页
• 分类号: R58

摘要

<strong>Aim</strong>: Evaluation of the occurrence of glucose intolerance after 34 - 36 weeks in pregnant mothers attending the Teaching Hospital, Peradeniya. <strong>Materials & Method</strong>: This is a descriptive cross-sectional study carried out from October 2017 to March 2018 among 183 pregnant mothers attending antenatal clinic at Teaching Hospital Peradeniya. After informed consent a repeat Oral Glucose Tolerance Test (OGTT) was done among the pregnant mothers, at period of amenorrhoea of 34 - 36 weeks, whose initial OGTT values were normal. Gestational diabetes was diagnosed according to the NICE guideline cut off values and the percentage of late occurrence of Gestational diabetes (GDM) was analyzed. <strong>Results</strong>: Mean age of the population was 29.1 years and the age range in this group was 18 to 45 years and the majority (73.9%) of women were primipara. There were 3.3% of teenage pregnancies and 14% of mothers were over 35 years. Majority (59.7%) of mothers underwent repeat OGTT test at 34 weeks of gestation and the rest (40.3%) underwent test between 34 to 36 weeks of gestation. Although the mean BMI was 23.74, 9.7% of mothers were obese (>30 kg/m2), 30.3% of mothers were pre-obese (25.0 - 29.9 kg/m2). 8.2% of mothers were diagnosed with Gestational diabetes at 34 - 36 weeks whose initial OGTT values were normal.<strong> Conclusion</strong>: In view of reducing feto-maternal morbidity and mortality, considering a repeat OGTT at a later gestation (34 - 36 weeks of gestation) should be considered in mothers, whose initial OGTT values are normal as Sri Lanka is a high risk country for GDM. <strong>Clinical Significance</strong>: The study may play an important role in guideline alteration process and screening for gestational diabetes in Sri Lankan set-up.