ADAMTS-8 Activity in Synovial Cells in Patients with Rheumatoid Arthritis

• 作者: Engin Deveci Murat Baloğlu Şenay Deveci
• 来源期刊: 风湿病与自身免疫疾病期刊(英文)
• 学科: 数学
• 关键词: Romatoid Artrit Sinovial Fluid ADAMTS-8
• 年，卷（期）: 2020,（3）
• 页码范围: 125-131
• 页数: 7页
• 分类号: O17

摘要

Rheumatoid arthritis (RA), chronic, autoimmune causing joint stiffness, pain, fatigue and functional disorders is a disease.<span><span><span style="font-family:;" "=""> </span></span></span><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;">The aim of this study is to invest</span><span style="font-family:Verdana;">igate the presence of ADAMTS-8 expression in cells in synovial fluid in rheumatoid arthritis patients</span></span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">. </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">Patients with active RA were aspirated with</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> arthro synthesis from the knee joint. Blood samples were taken from the patients at the same time, plasma samples were separated. Patients with sinovial fluid treated between 2019-2020 year in the Gazi Ya<span style="white-space:nowrap;">&#351;</span>argil Hospital Physical Therapy and Rehabilitation Clinic were involved in the study that was consulted with knee pain and difficulty in performing their daily activities. Informed consent form was obtained from all of the patients</span></span></span><span><span><span style="font-family:;" "=""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">(10 RA and 10 patients).</span></span></span><span><span><span style="font-family:;" "=""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">CRP, RF and ESH results were statistically evaluated in patients with Control and Rheumatoid arthritis.</span></span></span><span><span><span style="font-family:;" "=""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="fon