Primary small cell neuroendocrine carcinoma of the right posterior tongue

• 作者: Hang-Cheng Zhou Hui Peng Yu Zhou Zhi-Hong Zhang
• 来源期刊: 世界荟萃分析杂志
• 学科: 医学
• 关键词: Small cell carcinoma Neuroendocrine carcinoma Oral cavity Head and neck EXTRAPULMONARY
• 年，卷（期）: 2020,（4）
• 页码范围: 285-291
• 页数: 7页
• 分类号: R73

摘要

Small cell neuroendocrine carcinoma(SNEC)is an extremely aggressive tumor and mainly occurs in the lung.Primary extra-pulmonary SNEC is rare.To date,only 11 primary SNECs occurring in the oral cavity have been reported in the English literature.We describe a case of primary SNEC of the right posterior tongue in a 46-year-old man.The patient had stage IVA disease and received adjuvant chemotherapy,followed by radical surgery and radiotherapy.He remained tumor-free for 20 mo before death due to gastrointestinal metastasis.The relevant literature on the 11 previously reported patients was reviewed,and the clinical features,histopathological characteristics,differential diagnosis and therapeutic strategies of this rare tumor were analyzed.