<i>Baccaurea ramiflora</i>: Isolation of Aldehydes and in Vitro Biological Investigations

• 作者: Monira Ahsan
• 来源期刊: 药理与制药(英文)
• 学科: 化学
• 关键词: Baccaurea ramiflora ALDEHYDE NMR Spectroscopy ANTIOXIDANT CYTOTOXICITY
• 年，卷（期）: ylyzyyw_2020,（7）
• 页码范围: 147-157
• 页数: 11页
• 分类号: O62

摘要

The stem bark of </span><i><span style="font-family:Verdana;">Baccaurea ramiflora</span></i><span style="font-family:Verdana;"> was studied. Four aldehydes named as 3</span></span><span style="font-family:""> </span><span style="font-family:Verdana;">methoxy</span><span style="font-family:""> </span><span style="font-family:Verdana;">4</span><span style="font-family:""> </span><span style="font-family:Verdana;">hydroxy</span><span style="font-family:Verdana;">-</span><span style="font-family:Verdana;">cinnamaldehyde (coniferyl aldehyde);3,</span><span style="font-family:""> </span><span style="font-family:Verdana;">4,</span><span style="font-family:""> </span><span style="font-family:Verdana;">5</span><span style="font-family:""> </span><span style="font-family:Verdana;">trimethoxy</span><span style="font-family:""> </span><span style="font-family:Verdana;">cinnamaldehyde;3,</span><span style="font-family:""> </span><span style="font-family:Verdana;">4,</span><span style="font-family:""> </span><span style="font-family:Verdana;">5</span><span style="font-family:""> </span><span style="font-family:Verdana;">trimethoxy</span><span style="font-family:""> </span><span style="font-family:Verdana;">benzaldehyde and 3,4</span><span style="font-family:""> </span><span style="font-family:Verdana;">dimethoxy</span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">benzaldehyde) (veratraldehyde) have been isolated and then identified by NMR spectroscopy. All of them are first time reported for this plant. Here </span><i><span style="font-family:Verdana;">in vitro</span></i><span style="font-family:Verdana;"> biological investigations include antioxidant and cytotoxicity study. Among all fractions, the chloroform soluble fraction exhibited strong free radical scavenging activity having IC</span>_{<span style="font-family:Verdana;">50</span>}<span style="font-family:Verdana;"> value of 12.87 μg/ml compared to BHT (IC</span><sub><span style="font-family:Verdana;">50</spa