An Optimized Parameter of Hydrogel for a Seven-Day Release of a Drug

• 作者: Zixuan Jiang
• 来源期刊: 生物材料与纳米技术(英文)
• 学科: 数学
• 关键词: HYDROGEL Diffusion Rate Drug Release
• 年，卷（期）: 2020,（4）
• 页码范围: 237-244
• 页数: 8页
• 分类号: O17

摘要

Drug release is a crucial process in treatment. Conventional drug administration requires patient’s compliance and has the risk of overdosing. In order to control drug release, several potential materials are develo0ped. In this paper, we focus on hydrogel material and simulate drug release process in MATLAB. We optimize the parameter for a seven-day release of a drug. The results show that the diffusion coefficient at approximately 4.00E<span style="white-space:nowrap;">&#8722;</span>11 could ensure medicine to diffuse around 7 days and maintain its effects.