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摘要:
Propolis is a natural substance made from resins collected from trees and plants, and which bees combine with pollen, wax, and their own enzymes. It has a complex chemical composition that varies with the harvest season, vegetation type, bee species, and geographical region. Thanks to its components, it has valuable biological properties such as antifungal, antibacterial, anticancer, antiviral, and immunomodulatory activity. For this study, a sample of propolis harvested in April 2019 was used, which came from a bee native to Mexico (<span style="white-space:nowrap;"><i>Plebeia frontalis</i></span>) in whose geographical environment there are seven other native species. Canine distemper virus is an RNA virus that causes a systemic infection with high fatality rates in guests without protective immunity. In this work, the antiviral effect of <span style="white-space:nowrap;"><i>Plebeia frontalis</i></span> propolis on canine distemper virus was tested, administering it one hour before and simultaneously to infection. The antiviral effect was evaluated by determining cellular viability with the MTT assay. The results obtained show that this propolis has a statistically significant antiviral effect on both treatments, although it is slightly better when applied one hour before viral infection, so we can recommend it as an antiviral treatment in both domestic animals and human beings. There are currently few studies of the antiviral effect of propolis, this being the first study of a melliponium propolis in veterinary medicine.
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篇名 Evaluation of the Antiviral Activity of Propolis from Native Bees (&lt;i&gt;Plebeia frontalis&lt;/i&gt;) against Canine Distemper Virus
来源期刊 兽医学(英文) 学科 医学
关键词 PROPOLIS Vero Cells Antiviral Effect Meliponines
年,卷(期) 2020,(12) 所属期刊栏目
研究方向 页码范围 207-218
页数 12页 分类号 R51
字数 语种
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PROPOLIS
Vero
Cells
Antiviral
Effect
Meliponines
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相关学者/机构
期刊影响力
兽医学(英文)
月刊
2165-3356
武汉市江夏区汤逊湖北路38号光谷总部空间
出版文献量(篇)
118
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0
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0
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