The frontier studies about bio-medicine have a large blowout in recent years,so the translation of bio-medical literature is significant in terms of research.Under the guidance of Skopos theory,the authors analyze the use of different translation skills,such as,addition,omission,conversion,division,and combination,to solve the difficulties encountered in the process of translation.Such translations skills can help to overcome translation problems and achieve good communicative effect of scientific and technological texts.