Gastrointestinal lipomas are rare benign tumors and intussusception due to a gastrointestinal lipoma constitutes an infrequent clinical entity.Lipoma may develop as a benign tumor in all organs and rarely in large or small intestine ileal and colic lipoma.We reported two rare cases of bowel intusssception in adults.The invagination was diagnosed by computed tomography scan.Exploratory laparotomy revealed the intussusceptions secondary to a lipoma which was successfully treated with segmental intestinal resection.Since adult intussusception is frequently associated with malignant organic lesions,being aware of the differential diagnosis is important and timely surgical intervention paramount.The anatompatholy is essential for the diagnosis defintive and the search of malignitis signs.