Hepatic Hemangioendothelioma:An update

• 作者: Mayur Virarkar Melissa Taggart Mohammed Saleh Peeyush Bhargava Priya Bhosale Radwan Diab
• 来源期刊: 世界胃肠肿瘤学杂志:英文版(电子版)
• 学科: 医学
• 关键词: EPITHELIOID hemangioendotheliomas HALO SIGN LOLLIPOP SIGN ANGIOSARCOMA Cholangiocarcinomas Hepatocellular carcinoma
• 年，卷（期）: 2020,（3）
• 页码范围: 248-266
• 页数: 19页
• 分类号: R73

摘要

Primary epithelioid hemangioendotheliomas of the liver(EHL)are rare tumors with a low incidence.The molecular background of EHL is still under investigation,with WWTR1-CAMPTA1 mutation may function as a tumor marker.Commonly,this tumor is misdiagnosed with angiosarcoma,cholangiocarcinomas,metastatic carcinoma,and hepatocellular carcinoma(sclerosing variant).Characteristic features on imaging modalities such as ultrasound,computed tomography,magnetic resonance imaging and positron emission tomography/computed tomography guide in diagnosis and staging.The“halo sign”and the“lollipop sign”on computed tomography and magnetic resonance imaging are described in the literature.Currently,there are no standardized guidelines for treating EHL with treatment options are broad including:chemotherapy,ablation,surgery and liver transplantation with inconsistent results.