Prevalence and Endoscopic Findings of <i>Helicobacter pylori</i>Infection among Dyspeptic Patients in Kenya

• 作者: Ahmed Laving Allan Rajula Andrew Nyerere Catherine N. Mwangi Gunturu Revathi Rose Kamenwa Smita Devani Stephen Njoroge
• 来源期刊: 医学微生物学(英文)
• 学科: 医学
• 关键词: Helicobacter pylori DYSPEPSIA Esophagogastroduodenoscopy (EGD) Histopathological Examination
• 年，卷（期）: 2020,（4）
• 页码范围: 233-242
• 页数: 10页
• 分类号: R57

摘要

<b><span style="font-family:Verdana;">Background:</span></b><span style="font-family:""> <i><span style="font-family:Verdana;">Helicobacter</span></i> <i><span style="font-family:Verdana;">pylori</span></i><span style="font-family:Verdana;"> is the most common cause of chronic human infections worldwide with the highest reported prevalence in Africa. It is associated with numerous upper gastrointestinal diseases such as gastritis, peptic ulcers, and gastric cancer. Endoscopic findings in the stomach usually associated with </span><i><span style="font-family:Verdana;">Helicobacter</span></i> <i><span style="font-family:Verdana;">pylori</span></i><span style="font-family:Verdana;"> infections include gastritis and gastro-esophageal reflux disease (GERD), however, these findings are suggestive but not diagnostic of </span><i><span style="font-family:Verdana;">Helicobacter</span></i> <i><span style="font-family:Verdana;">pylori</span></i><span style="font-family:Verdana;"> infection. </span><b><span style="font-family:Verdana;">Methods:</span></b><span style="font-family:Verdana;"> This was a prospective study conducted between January 2018 and February 2019 at the Aga Khan University Hospital where dyspeptic patients scheduled for gastroduodenoscopy were enrolled. These patients were evaluated for </span><i><span style="font-family:Verdana;">Helicobacter</span></i> <i><span style="font-family:Verdana;">pylori</span></i><span style="font-family:Verdana;"> infection by rapid urease test, culture and histopathology. Diagnostic findings and patient history collected from medical files w</span></span><span style="font-family:Verdana;">ere</span><span style="font-family:""><span style="font-family:Verdana;"> documented and data analyzed. </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> A total of 487 dyspeptic patients undergoing esophagogastroduodenoscopy (EGD) were enrolled in the study and 199 dyspeptic patients were positive for </span><i><span style="font-family:Verd