Synthesis and Fungicidal Activity of Chlorothalonil Derivatives

• 作者: Han Jintao Jiang Aizhong Li Jintao Wang Yingxiu
• 来源期刊: Plant Diseases and Pests(植物病虫害研究:英文版)
• 学科: 化学
• 关键词: CHLOROTHALONIL Novel compound SYNTHESIS Fungicidal activity
• 年，卷（期）: 2020,（3）
• 页码范围: 15-17
• 页数: 3页
• 分类号: O62

摘要

[Objective]The paper was to develop a novel fungicide with high efficacy and low toxicity.[Method]Chlorothalonil was used as the parent structure,and its 4-position substituent was converted to amino group.Totally 12 amide compounds not reported in the literature were designed and synthesized.Their structures were conformed by 1H NMR.[Result]The preliminary bioassay test showed that compounds JTCN-01,JTCN-05 and JTCN-07 had good control effect on corn rust at the concentration of 200 mg/L,and the control effect of compound JTCN-05 reached 95%.[Conclusion]Some chlorothalonil derivatives had the potential for further development.