<strong>Background:</strong><span><span><span style="font-family:""><span style="font-family:Verdana;"> The increasing life expectancy of people worldwide will signify that oncologists everywhere will be faced with many difficult decisions regarding treatment options in the elderly population with cancer. These patients carry specific challenges that should be discussed. </span><b><span style="font-family:Verdana;">Aim:</span></b><span style="font-family:Verdana;"> To report the clinical case of an elderly patient with a metastatic colorectal cancer with a sustained complete response and reflect on the particularities on this special population. </span><b><span style="font-family:Verdana;">Clinical case:</span></b><span style="font-family:Verdana;"> In 2009</span></span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">,</span></span></span><span><span><span style="font-family:""><span style="font-family:Verdana;"> an 80-year-old man presents with colorectal cancer, undergoes surgery and intraoperatively a peritoneal implant is resected. He is deemed fit for chemotherapy and is treated with 8 cycles of capecitabine. After a 10-year follow-up, he remains with no evidence of disease. </span><b><span style="font-family:Verdana;">Conclusion:</span></b><span style="font-family:Verdana;"> Chronological age is insufficient to establish a treatment plan;oncologists must evaluate the patient multidimensionally and develop personalized options for the therapy and follow-up of older individuals.</span></span></span></span>