Missing perilymph but leaking blood-endolymph and vestibulocochlear nerve barriers in idiopathic sudden sensorineural hearing loss: A case study

• 作者: Jing Zou
• 来源期刊: 中华耳科学杂志（英文版）
• 年，卷（期）: 2020,（4）
• 所属期刊栏目: Short Communication
• 页码范围: 171-173
• 页数: 3页
• 语种: 英文

摘要

Objectives: To evaluate the pathological changes in the blood-perilymph, blood-endolymph, and blood-nerve barriers of a patient with idiopathic sudden sensorineural hearing loss (SSNHL).Methods: Potential ossification or fibrosis in the inner ear was evaluated using temporal bone CT and MRI acquired using the 3-dimensional T2-weighted sampling perfection with application-optimized con-trasts using a flip angle evolution sequence. Pathological changes in the barriers were analyzed by MRI obtained 4 h after a single-dose intravenous injection of gadolinium chelate using a medium inversion-time inversion recovery imaging with magnitude reconstruction sequence. Results: The perilymph was absent, while significant enhancements of the vestibulocochlear nerve and the endolymphatic compartments were detected. Conclusion: Significant injuries in the blood-endolymph and blood-vestibulocochlear nerve barriers and disabled perilymph production may contribute to the development of SSNHL with poor response to treatments.