Evading the host response:Staphylococcus"hiding"in cortical bone canalicular system causes increased bacterial burden

• 作者: Stephen D.Zoller Vishal Hegde Zachary D.C.Burke Howard Y.Park Chad R.Ishmael Gideon W.Blumstein William Sheppard Christopher Hamad Amanda H.Loftin Daniel O.Johansen Ryan A.Smith Marina M.Sprague Kellyn R.Hori Samuel J.Clarkson Rachel Borthwell Scott I.Simon Jeff F.Miller Scott D.Nelson Nicholas M.Bernthal
• 来源期刊: 骨研究（英文版）
• 年，卷（期）: 2020,（4）
• 所属期刊栏目: ORIGINAL ARTICLES
• 页码范围: 447-457
• 页数: 11页
• 语种: 英文

摘要

INTRODUCTION Over the past four decades,"limb salvage"surgery, or surgery in which bulk reconstruction is needed after a large amount of bone is removed for oncologic, infectious, or traumatic pathology, has become more commonplace than amputation. While debates have raged in the clinical communities as to whether metal1–2 or allograft bone3–5 provided a better material for reconstruction, most of the evidence provided was focused on mechanical function and durability.