Frequency and Outcome of Meconium Aspiration Syndrome in Babies Born with Meconium-Stained Liquor at Secondary Care Hospital in Pakistan: A Case Series Study

• 作者: Khadija Humayun
• 来源期刊: 儿科学期刊(英文)
• 学科: 数学
• 关键词: Meconium Aspiration Syndrome MORTALITY NEONATES OUTCOME
• 年，卷（期）: 2020,（3）
• 页码范围: 381-391
• 页数: 11页
• 分类号: O17

摘要

<strong>Background:</strong><span style="font-family:;" "=""><span style="font-family:Verdana;"> Meconium aspiration syndrome (MAS) in the newborn is characterized by hypoxia, hypercapnia, and acidosis. MAS is a leading cause of morbidity and mortality in neonates. The primary objective of this study was to estimate the frequency of meconium aspiration syndrome (MAP) in babies born with meconium-stained liquor. The secondary outcome was to estimate the meconium aspiration syndrome;in terms of hospital stay, complications, and mortality. </span><b><span style="font-family:Verdana;">Methods: </span></b><span style="font-family:Verdana;">The study was done at Aga Khan Maternal and Child Care Centre, Hyderabad, Pakistan. Study design was case series and the duration of the study was of 6 months. All patients who fulfilled the inclusion criteria were included in the study after taking informed written consent. A brief history was taken, clinical examination was done and laboratory investigations were sent to the institutional laboratory. Study outcomes were measured from this data </span><i><span style="font-family:Verdana;">i</span></i><span style="font-family:Verdana;">.</span><i><span style="font-family:Verdana;">e</span></i><span style="font-family:Verdana;">. MAS, its complications, mortality, and a number of days in the hospital. </span><b><span style="font-family:Verdana;">Results: </span></b><span style="font-family:Verdana;">A total of 87 babies</span><b><i> </i></b><span style="font-family:Verdana;">born with meconium-stained liquor at secondary care hospital were included. A total of 45 patients (52%) were males and 42 patients (48%) were females with a mean gestational age of babies 38.896 </span></span><span style="font-family:;" "=""><span style="font-family:Verdana;">± </span><span style="font-family:Verdana;">1.210 weeks. The mean Apgar score at 5 minutes was 8.896 </span><span style="font-family:Verdana;">± </span><span><span style="font-family:Verdana;">0.404. MAS was present in 13 patients (14.9%)