Clinical andTransmission Characteristics of COVID-19-A Retrospective Study of 25 Cases from a Single Thoracic Surgery Department

• 作者: Le-qun LI Ni ZHANG Qi WANG Shu PENG Wei PING Xiang-ning FU Yang-kai LI
• 来源期刊: 当代医学科学(英文)
• 学科: 医学
• 关键词: corona virus disease 2019 SARS-CoV-2 nosocomial infection
• 年，卷（期）: ddyxkxyw,（2）
• 页码范围: 295-300
• 页数: 6页
• 分类号: R65

摘要

The outbreak of corona virus disease 2019(COVID-19)imposes a major challenge in managing patients undergoing surgical operation.In this study,we analyzed clinical and transmission features of 25 cases of COVID-19 from a single thoracic department,including 13 patients and 12 health care staff.There were 13 males and 12 females.The median age of the patients was 61(range:51 to 69)years.The median age of the health care staff was 35(range:22 to 51)years.By the end of follow-up date(Mar.3,2020),there were 16 non-severe cases(64%)and 9 severe cases(36%),5 cases were dead(20%).Nineteen(76%)of the infected cases were confirmed by SARS-CoV-2 nucleic acid test,the rest were clinically diagnosed as suspected COVID-19 cases,and 19(76%)of the infected cases had positive exposure history.We found that COPD was significantly associated with severity and death(P-0.040,and P=0.038,respectively),and chest operation was significantly associated with death for COVID-19 patients(P-0.039).A potential“super spreader"may be the source of the transmission before the implementation of quarantine and comprehensive protcction.It was concluded that COVID-19 is associated with poor prognosis for patients undergoing thoracic operation,especially for those with COPD.Implementation of comprehensive protective measures is important to control nosocomial infection.