Freezing the kinase signaling of breast cancer with transformable peptide nanoparticles

• 作者: Di-Wei Zheng Xian-Zheng Zhang
• 来源期刊: 中国科学:化学（英文版）
• 年，卷（期）: 2020,（8）
• 所属期刊栏目: HIGHLIGHTS
• 页码范围: 1021-1022
• 页数: 2页
• 语种: 英文

摘要

Protein kinases have been recognized as dominant regulators of all aspects of tumor progression, including tumorigenesis,proliferation, invasion, and metastasis [1].During the activation of protein kinases, the binding of ligands (e.g., epidermal growth factor, transforming growth factor-α, and amphiregulin) can cause dimerization, which promotes the cell growth and triggers a cascade of downstream signaling pathways.Considering the versatile role of protein kinases,targeting of protein kinases is currently one of the most successful strategies in the development of anti-cancer drugs.

作者信息

序号	姓名	单位	发文数	被引次数	H指数	G指数
1	Di-Wei Zheng		1	0	0.0	0.0
2	Xian-Zheng Zhang		1	0	0.0	0.0