Assessment of EEG Changes in Neonatal Sepsis at Al-Zahraa University Hospital’s NIC Unit

• 作者: Asmaa Abd El Wakeel Ibrahim Marwa El-Hady Abd El Moneim Sara Tarek Mohamed Mohamed Zeinab Farag Oshaiba
• 来源期刊: 儿科学期刊(英文)
• 学科: 医学
• 关键词: Background Abnormalities ELECTROENCEPHALOGRAM Neurological Complication Sepsis Spike Seizures
• 年，卷（期）: 2020,（3）
• 页码范围: 493-503
• 页数: 11页
• 分类号: R74

摘要

<strong>Background:</strong><span style="font-family:""><span style="font-family:Verdana;"> EEG is one of the most sensitive instrumental techniques for identifying sepsis-related neurological complications and a valuable tool in the ICU when clinical assessment is difficult. </span><b><span style="font-family:Verdana;">Aim of the Study:</span></b><span style="font-family:Verdana;"> To detect EEG changes in neonates with evidence of sepsis.</span><a name="_Toc508467354"></a> <b><span style="font-family:Verdana;">Patients and Methods</span></b><b><span style="font-family:Verdana;">:</span></b><span style="font-family:Verdana;"> This was a prospective observational study for detecting EEG changes in cases of proven neonatal sepsis. This study was conducted at the NICU of Al Zahraa University Hospital for a period from October 2019 to March 2020. Our studied neonates were 50. This study included full-term newborns (37 to 42 weeks of gestational age) with clinical and laboratory evidence of sepsis (early and late onset). Neonatal birth asphyxia, jaundice, congenital malformations, suspected inborn error of metabolism and neonates electrolytes disturbances were excluded from the study. We record EEG changes during 20 min By an electroencephalogram</span><b> </b><span style="font-family:Verdana;">(EEG) with abioelectric amplifier (Deltamed, Bourgogne), (Philips) Screen.</span><b> <span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> Among our studied neonates (neonates with evidence sepsis), 44.0% developed clinical seizures, 81% of the seizures group had abnormal EEG, 35.7% of No seizures group had abnormal EEG. Among our studied neonates, 56% had abnormal EEG EEG abnormalities were as follow, 26%/ had low voltage, 30% had spikes, 22% had sharp waves. </span><b><span><span style="font-family:Verdana;">Conclusion:</span><i> </i></span></b><span style="font-family:Verdana;">About 35% (one third) of neonates who didn’t develop clinical seizures had abnormal EEG, suggesting a poor cor