Diagnostic and prognostic value of cardiac imaging in amyloidosis

• 作者: Alberto Bouzas-Mosquera Gonzalo Barge-Caballero Jose Manuel Vazquez-Rodriguez Jose Maria Larrañaga-Moreira Maria Generosa Crespo-Leiro Rafael Vidal-Perez Rafaela Soler-Fernandez Raquel Vázquez-García
• 来源期刊: 世界心脏病学杂志:英文版(电子版)
• 学科: 医学
• 关键词: Cardiac imaging techniques Transthyretin cardiac amyloidosis Immunoglobulin light-chain amyloidosis ECHOCARDIOGRAPHY Magnetic resonance imaging Nuclear imaging
• 年，卷（期）: 2020,（12）
• 页码范围: 599-614
• 页数: 16页
• 分类号: R59

摘要

Amyloidosis is an infiltrative disease caused by extracellular protein deposition that has accumulated a lot of scientific production in recent years.Different types of amyloidosis can affect the heart.Transthyretin amyloidosis and light chain amyloidosis are the two most common types of cardiac amyloidosis.These entities have a poor prognosis,so accurate diagnostic techniques are imperative for determining an early therapeutic approach.Recent advances in cardiac imaging and diagnostic strategies show that these tools are safe and can avoid the use of invasive diagnostic techniques to histological confirmation,such as endomyocardial biopsy.We performed a review on the diagnostic and prognostic implications of different cardiac imaging techniques in cardiac amyloidosis.We mainly focus on reviewing echocardiography,cardiac magnetic resonance,computed tomography and nuclear imaging techniques and the different safety measurements that can be done with each of them.