Prevalence of Carotid Atheromatous Plaques in Pre-Dialysis Chronic Kidney Disease Patients in South East, Nigeria

• 作者: C. Uche Ibewuike Chukwuemeka O. Eze Ifeoma I. Ulasi Monday U. Nwobodo Olaronke F. Afolabi
• 来源期刊: 心血管病(英文)
• 学科: 医学
• 关键词: Carotid Plaques CKD Predialysis NIGERIA
• 年，卷（期）: xxgbyw_2020,（9）
• 页码范围: 639-647
• 页数: 9页
• 分类号: R69

摘要

<strong>Background:</strong><span style="font-family:Verdana;"> Chronic kidney disease (CKD) patients have considerably high atherosclerotic changes which predict cardiovascular events</span><span style="font-family:Verdana;">;</span><span style="font-family:Verdana;">hence</span><span style="font-family:Verdana;">,</span><span style="font-family:;" "=""><span style="font-family:Verdana;"> this study evaluated the prevalence of carotid atherosclerotic plaques in pre-dialysis CKD patients at a tertiary institution in south-east, Nigeria. </span><b><span style="font-family:Verdana;">Materials</span></b><span style="font-family:Verdana;"> </span><b><span style="font-family:Verdana;">and</span></b><span style="font-family:Verdana;"> </span><b><span style="font-family:Verdana;">Method: </span></b><span style="font-family:Verdana;">107 pre-dialysis CKD patients were consecutively recruited for the study. 81 subjects who were screened and had no kidney disease served as control. The control group was sex and age matched with the CKD patients. A pre-tested questionnaire was administered to all participants and physical examination was done. Presence of atheromatous plaques was assessed using doppler ultrasound at 3 sites—distal common carotid artery (CCA), the internal carotid artery (ICA) and the carotid bulb by a single skilled radiologist specialized in doppler ultrasound. </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> Atheromatous plaques were significantly increased in CKD patients. 14.2% of CKD patients had atheromatous plaques versus 2.5% in the control group (p value < 0.05). Commonest site of occurrence was at the common carotid artery (CCA-7.5% versus ICA-4.7% versus bulb 1.8%). </span><b><span style="font-family:Verdana;">Conclusions:</span></b><span style="font-family:Verdana;"> Atheromatous plaques are prevalent in CKD patients. It is recommended that carotid doppler ultrasound should be done in CKD patients to identify patients for possible intervention