Candida Colonization among Neonates with Low Birth Weight: There Is Much More to Explore

• 作者: Adolfine Hokororo Benard Modest Florentina Mashuda Martha F. Mushi Stephen E. Mshana Vitus Silago Wilhelmina Mussa
• 来源期刊: 儿科学期刊(英文)
• 学科: 数学
• 关键词: Candida Colonization C. albicans C. glabrata Oral
• 年，卷（期）: 2020,（4）
• 页码范围: 626-634
• 页数: 9页
• 分类号: O17

摘要

<strong>Background</strong><span><span><span style="font-family:;" "=""> <b><span style="font-family:Verdana;">and</span></b> <b><span style="font-family:Verdana;">Objectives:</span></b><span style="font-family:Verdana;"> Candida colonization in neonates with low birth weight is reported to be the first step for invasive candidiasis. This study was designed to describe the patterns of </span><i><span style="font-family:Verdana;">Candida</span></i><span style="font-family:Verdana;"> spp. colonizing neonates with low birth weight in Mwanza, Tanzania to provide baseline information for future studies in this field. </span><b><span style="font-family:Verdana;">Methodology:</span></b><span style="font-family:Verdana;"> The hospital based cross sectional study was conducted between January 2019 and April 2019 among neonates with low birth weight. Clinical and social demographic data were collected using interview guide questionnaire. Oral and umbilical</span></span></span></span><span><span><span style="font-family:;" "=""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">rectal swabs were collected on </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">the </span></span></span><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;">first and seventh day of life to assess </span><i><span style="font-family:Verdana;">Candida</span></i><span style="font-family:Verdana;"> spp. colonization status. Data were analyzed using STATA version 13 following the study objectives. </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> A total of 320 neonates with median body weight of 1600 [IQR 1000 - 2000] grams were enrolled. Prevalence of </span><i><span style="font-family:Verdana;">Candida</span></i><span style="font-family:Verdana;"> spp. colonization on either oral, umbilical or rectum was 16.2% (52/320). A tot