A Comparative Study on the Effect of <i>Massularia acuminata</i>Fractions against Bacterial and Fungal Isolates from the Oral Cavity

• 作者: Adesayo Olufunmi Olusola
• 来源期刊: 健康(英文)
• 学科: 农学
• 关键词: Massularia acuminata Antimicrobial Assay Ethanolic and Methanolic Extracts TETRACYCLINE
• 年，卷（期）: 2020,（7）
• 页码范围: 904-913
• 页数: 10页
• 分类号: S43

摘要

The research aimed at carrying out a comparative study on the effect of <i>Massularia</i> <i>acuminata</i> fractions against bacterial and fungi isolates from the oral cavity. The Antimicrobial assay was carried on the following test organism;<i>Staphylococcus</i> <i>aureus</i>, <i>Klebsiella</i> <i>pnuemoniae</i>,<i>Bacillus</i> <i>subtilis</i> and <i>Escherichia</i> <i>coli</i> and <i>Enterobacter</i> <i>aerogenes</i>. From antifungal result, it was observed that the highest inhibition was observed in the ethanolic extract of <i>Massularia</i> <i>acuminata</i> on <i>Rhyzopus</i> <i>stolonifer</i>, <i>Candida</i> <i>albican</i> and <i>Fusarium</i> <i>solani</i>. The ethanolic and methanolic extracts were also observed from the results to have an intermediate sensitivity to <i>Aspergillus</i> <i>favus</i>, <i>Candida</i> <i>tropicalis</i>, <i>Can</i><i>dida</i> <i>albican</i>, <i>Rhyzopus</i> <i>stolonifer</i>, <i>Fusarium</i> <i>solani</i>, while it was observed to be resistant to <i>Fusarium</i> <i>solani</i>, <i>Rhyzopus</i> <i>stolonifer</i>, <i>Candida</i> <i>tropicalis</i>, <i>Aspergillus</i> <i>favus</i> for all the partitions of the extracts. From the antifungal effect of the <i>M</i>. <i>acuminata</i> fractions, it could be inferred that the ethanolic and methanolic extracts were quite effective in the inhibition of the fungi infections and the methanolic extract proved very infective on <i>Candida</i> <i>albican</i>, <i>Rhyzopus</i> <i>stolonifer</i> <i>and</i> <i>Fusarium</i> <i>solani</i>. From the result of the antibacterial effect of <i>M</i>. <i>acuminata</i> fractions, the highest inhibition was observed by the methanolic extract of <i>Massularia</i> <i>acuminata</i> against all the Gram negative bacteria and <i>Staphylococcus</i> <i>aureus</i>. Also the aqueous extract also had a less sensitivity against all the test microbes, as all proved resistant. It could be inferred that the fractions of the extracts were unable to inhibit the growth of the strain of gram positive bacteria and probably, the