Probing for Conditioned Hallucinations Through Neural Activation in a Ketamine Mouse Model of Schizophrenia

• 作者: Jenny L.Wu Michela Gallagher Ming Teng Koh Rebecca P.Haberman
• 来源期刊: 神经科学通报（英文版）
• 年，卷（期）: 2020,（8）
• 所属期刊栏目: Letters to the Editor
• 页码范围: 937-941
• 页数: 5页
• 语种: 英文

摘要

Dear Editor, When two stimuli such as a tone and a visual stimulus are repeatedly presented together, individuals diagnosed with hallucinations tend to report hearing the tone subsequently in response to the visual stimulus alone [1].Such conditioned hallucinations involved evoked sensory representations as evidenced by increased neural activation in tone-responsive brain regions during the conditioned hallucinations.These and other observations underscore the importance of prior associative experiences in driving hallucinatory perception, and reflect new efforts to conceptualize and understand psychosis from a cognitive perspective.