Stimulated Raman scattering signal generation in a scattering medium using self-reconstructing Bessel beams

• 作者: JI-XIN CHENG LIN WANG PENG LIN XINYU WANG XUELI CHEN YONGHUA ZHAN
• 来源期刊: 光子学研究:英文版
• 学科: 物理学
• 关键词: BESSEL BEADS destroyed
• 年，卷（期）: 2020,（6）
• 页码范围: 929-939
• 页数: 11页
• 分类号: O43

摘要

Scattering is a huge challenge for microscopic imaging.Indeed,it is difficult to observe target chemicals in scattering media by means of the current Gaussian beam-based stimulated Raman scattering(SRS)microscopy,since the tight focus of the Gaussian beam is destroyed after propagating through a certain distance.Bessel beams,featuring self-reconstructing property,may bring a solution to this problem.By combining Bessel beams with SRS microscopy,we can probe the SRS signal from a scattering medium.In this paper,using the beam propagation method,we first simulate the propagation of the Bessel beam as well as the generation and self-reconstruction of SRS signals.By adding glass beads along the beam propagation path in order to simulate scattering,the propagation of the Bessel beams and the generation of the SRS signals will change.Then,we design a series of simulations to investigate the influence of the size,position,number,and distribution of the added glass beads on the generation of the SRS signals.A preliminary experiment is also carried out to confirm the simulation predictions.Results demonstrate that the SRS signals can be generated or be recovered at a certain depth in scattering media,and that such signals are greatly affected by the parameters of the scatters.