Surgical Treatment of Central Giant Cell Granuloma with Carnoy’s Solution

• 作者: José Luis Calvo-Guirado Mariano Escudero-Pinel Miguel Ángel Garcés-Villalá Sergio David Rico
• 来源期刊: 生物科学与医学(英文)
• 学科: 医学
• 关键词: Central Giant Cell Granuloma Carnoy’s Solution Conservative Surgical Treatment
• 年，卷（期）: 2020,（8）
• 页码范围: 67-78
• 页数: 12页
• 分类号: R73

摘要

A 25-year-old woman presented a unilateral mandibular swelling, after laboratory analysis, radiological studies and aspiration puncture biopsy, the pathological diagnosis of Central Giant Cell Granuloma was made. Radiographically, the multilocular lesion involved the left lower first molar and was 30 mm long by 20 mm high. Dental extraction of the molar involved with forceps and exeresis in toto of the tumor were performed using a Volkmann cutting curette. The tumor made up of 90% vascular tissue produced intra-surgical bleeding that made visibility difficult. The bone bed curettage was aggressive except for its base in direct contact with the inferior dental nerve. Subsequently, to avoid recurrence, the surgical protocol includes a double irrigation with Carnoy’s solution, (fixative composed of 60% ethanol, 30% chloroform and 10% glacial acetic acid 98%) for 5 minutes that produces chemical cauterization. Finally, it was washed with physiological solution and the cavity was filled with iodoformed gauze. The gauze was exchanged and removed gradually over three weeks for second intention healing. This case is presented to demonstrate that inexpensive chemical treatment can be safely used for outpatient surgery under local anesthesia. Because Carnoy’s solution achieved control of intraoperative bleeding, allowed bone healing and prevented recurrence of the lesion in clinical radiographic follow-up for 15 years.