Impact of Prophylactic Betamethasone Indication on the Neonatal Outcome in 38-Week Pregnancies Prior to Elective Cesarean Section

• 作者: Alvaro Sepúlveda-Martínez Enrique Valdés M Enrique Valdés Rubio Javiera Urquieta Pamela Socías
• 来源期刊: 妇产科期刊(英文)
• 学科: 医学
• 关键词: BETAMETHASONE CORTICOSTEROIDS Elective Cesarean Section Respiratory Complications Respiratory Distress Syndrome Transitory Tachypnea
• 年，卷（期）: 2020,（10）
• 页码范围: 1396-1401
• 页数: 6页
• 分类号: R72

摘要

<strong>Objective: </strong><span style="font-family:Verdana;">To assess whether the use of prenatal betamethasone in pregnancies with elective Caesarean section (C-section) at 38 weeks ha</span><span style="font-family:Verdana;">s</span><span style="font-family:""><span style="font-family:Verdana;"> a similar risk of adverse neonatal respiratory outcomes than elective C-section at 39 weeks. </span><b><span style="font-family:Verdana;">Methods:</span></b><span style="font-family:Verdana;"> Retrospective cohort study of pregnant patients with singleton pregnancies and elective C-section at term in a one-year period. Cases were C-section at 38 weeks of gestation with a complete course of betamethasone started 48-hours before. As a control group, pregnancies with a C-section at 39 weeks without betamethasone were included. </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> During the study period, 186 patients were included. Of these, 91 were delivered at 38 weeks and 95 at 39 weeks. There were no significant differences in maternal age and parity. Moreover, there were no significant differences in respiratory complications (respiratory distress syndrome [RDS] = 0% vs 1.1%;p</span></span><span style="font-family:""> </span><span style="font-family:Verdana;">=</span><span style="font-family:""> </span><span style="font-family:Verdana;">1.0, transitory tachypnea [TT] = 0% vs 0%) and admission to Neonatal Intensive Care Unit (NICU) (8.8% vs 6.3%;p</span><span style="font-family:""> </span><span style="font-family:Verdana;">=</span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">0.7) between deliveries at 38 weeks and 39 weeks, respectively. </span><b><span style="font-family:Verdana;">Conclusion:</span></b><span style="font-family:Verdana;"> Prophylactic use of betamethasone in early term pregnancies who undergo an elective C-section at 38 weeks is associated with similar adverse neonatal respiratory outcomes than patien