Differentiation of Expression Profiles of SREBF1 and SREBF2 Gene in Chicken

• 作者: Chaowu YANG Chunlin YU Hengyong XU Huadong YIN Huarui DU Mohan QIU Qing ZHU Qingyun LI Xiaoling ZHAO Xiaosong JIANG Yan WANG Zengrong ZHANG
• 来源期刊: 农业生物技术:英文版
• 学科: 医学
• 关键词: CHICKEN SREBF1 SREBF2 Differential expression
• 年，卷（期）: 2020,（5）
• 页码范围: 90-93
• 页数: 4页
• 分类号: R73

摘要

Sterol regulatory element-binding factor-1 and-2(SREBF1 and SREBF2)are important transcription factors involved in the regulating lipid homeostasis.Based on the essential role of SREBF1 and SREBF2,we measured the mRNA expression levels of the two genes in six various tissues at different growth points.Our results showed that the SREBF1 and SREBF2 were expressed in all six tissues examined in Erlang mountainous chicken(SD02)at 42 d,and were expressed abundantly in the uropygial gland and liver,with relatively lowest levels of expression in the abdominal fat,sebum cutaneum and leg muscle.The expression ratio of SREBF1 and SREBF2 in breast muscle,leg muscle,sebum cutaneum and uropygial gland exhibited a"decline-rise"trend.However,in liver,the expression ratio of these two genes exhibited a"decline-rise-decline"trend.Meanwhile,the expression level of SREBF1 gene of all tissues was lower than that of SREBF2 except for uropygial gland.The findings will provide important references for further function investigation of the two genes involved in fat deposition in chickens.