A Novel Potassium Nanosensor Powers up the Detection of Extracellular K+ Dynamics in Neuroscience
A Novel Potassium Nanosensor Powers up the Detection of Extracellular K+ Dynamics in Neuroscience
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摘要:
Potassium ions(K+),the pivotal cations for membrane potential,are particularly important for maintaining the physiological function of neurons[1].When the concen-tration of extracellular K+([K+]o)is pathologically changed,the intrinsic neuronal excitability and synaptic transmission are also altered,which have profound impli-cations for many neurological disorders such as epilepsy,Parkinson's disease,and emotional disorders[2-4].