Pd-Catalyzed Site-Selective Borylation of Simple Arenes via Thianthrenation

• 作者: Xiao-Yue Chen Yu-Hao Huang Jian Zhou Peng Wang
• 来源期刊: 中国化学（英文版）
• 年，卷（期）: 2020,（11）
• 所属期刊栏目: Concise Reports
• 页码范围: 1269-1272
• 页数: 4页
• 语种: 英文
• DOI: 10.1002/cjoc.202000212

摘要

Site-selective borylation of simple arenes was realized in one pot via an electrophilic thianthrena-tion/Pd-catalyzed borylation sequence.The key to achieve this operatically simple process is the use of Pd catalysis,which could tolerate the solvent and acidic conditions used in the thianthrenation step.This protocol features mild conditions,broad functional group tolerance,and simple manipulations,and is suitable for late-stage functionalization of a wide range of pharmaceuticals and complex bioactive molecules.