Research progress of microRNA in the regulatory mechanism of hypoxic-ischemic encephalopathy

• 作者: Chun-Yang Liu Hisham Hui Xu Hui-Qin Zeng Min Liu Yu-Chun Han Ze-Yuan Liu
• 来源期刊: 海南医科大学学报（英文版）
• 年，卷（期）: 2020,（24）
• 所属期刊栏目: Review and lectures
• 页码范围: 65-70
• 页数: 6页
• 语种: 英文

摘要

MicroRNA (miRNA) plays a key role in the molecular regulation of neurological diseases, and the molecular mechanism of miRNA is closely related to the occurrence and development of hypoxic-ischemic encephalopathy. Recently, it has been reported that various miRNA molecules can inhibit target mRNA and even degrade target mRNA by changing the complete complementary or incomplete complementary binding to the target mRNA. Therefore, miRNA is of great significance for the study of mRNA related to hypoxic ischemic encephalopathy. This article briefly reviews the molecular mechanisms, functions and regulation of miRNAs on hypoxic-ischemic encephalopathy.