Hazarders of Smoking and <i>Helicobacter pylori</i>Infection on Gastric Mucosa among Egyptian Patients with Dyspepsia

• 作者: Rasha I. Salama Mahmoud W. Emara Shimaa M. El Sharawy
• 来源期刊: 肠胃病学期刊(英文)
• 学科: 医学
• 关键词: DYSPEPSIA Helicobacter pylori SMOKING Egypt
• 年，卷（期）: 2021,（1）
• 页码范围: 1-15
• 页数: 15页
• 分类号: R57

摘要

<b><span style="font-family:Verdana;">Background:</span></b><span style="font-family:""><span style="font-family:Verdana;"> Smoking is hazardous to almost any organ in the body and has a harmful effect on the gastric mucosa. </span><b><span style="font-family:Verdana;">Objective:</span></b><span style="font-family:Verdana;"> The main goal of this study was to evaluate the synergistic effect of smoking and </span><i><span style="font-family:Verdana;">H</span></i><span style="font-family:Verdana;">.</span><i><span style="font-family:Verdana;"> pylori</span></i><span style="font-family:Verdana;"> infection on gastric mucosal among dyspeptic Egyptian patients. </span><b><span style="font-family:Verdana;">Patients and Methods:</span></b><span style="font-family:Verdana;"> A cross-sectional study was conducted among 240 consecutive patients with dyspepsia who underwent upper endoscopy and histopathological examination of gastric biopsies at Zagazig and Tanta University Hospital with </span><i><span style="font-family:Verdana;">H</span></i><span style="font-family:Verdana;">.</span><i><span style="font-family:Verdana;"> pylori</span></i><span style="font-family:Verdana;">-positivity assessment by stool antigen and rapid urease test. </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> There were 60 smoker patients and 180 non-smoker patients. Erosive gastritis was more prevalent in smoker patients than non-smoker patients (46.7% versus 15.6%, p = 0.00). In </span><i><span style="font-family:Verdana;">H</span></i><span style="font-family:Verdana;">.</span><i><span style="font-family:Verdana;"> pylori</span></i></span><span style="font-family:Verdana;">-positive</span><span style="font-family:Verdana;"> patients (36.7% of all patient</span><span style="font-family:Verdana;">s</span><span style="font-family:Verdana;">), smokers were more prevalent than non-smokers in </span><span style="font-family:Verdana;">the </span><span style="font-family:Verdana;">development of intestin