Free Radical Scavenging, Enzyme Inhibitory and Anti-<i>Staphylococcus aureus</i>Properties of the Fruiting Bodies of <i>Ganoderma lucidum</i>, Lingzhi Mushroom

• 作者: Md. Moyan Uddin PK Mohammad Sayful Islam Shariful Haque Lutfa Akther Rumana Pervin
• 来源期刊: 药理与制药(英文)
• 学科: 数学
• 关键词: Ganoderma lucidum MUSHROOM Antioxidant Activity Enzyme Inhibitory Activity Anti-Staphylococcus aureus Activities
• 年，卷（期）: 2021,（3）
• 页码范围: 73-84
• 页数: 12页
• 分类号: O17

摘要

<span style="font-family:Verdana;">The current study evaluated the antioxidant, </span><i><span style="font-family:Verdana;">α</span></i><span style="font-family:Verdana;">-amylase inhibitory and anti-</span><i><span style="font-family:Verdana;">Staphylococcus</span></i> <i><span style="font-family:Verdana;">aureus</span></i><span style="font-family:Verdana;"> activities of the fruiting bodies of </span><i><span style="font-family:Verdana;">Ganoderma</span></i> <i><span style="font-family:Verdana;">lucidum</span></i><span style="font-family:Verdana;">. Methanolic extract of </span><i><span style="font-family:Verdana;">G.</span></i> <i><span style="font-family:Verdana;">lucidum</span></i><span style="font-family:Verdana;"> (MEGL) was investigated for its </span><i><span style="font-family:Verdana;">in</span></i> <i><span style="font-family:Verdana;">vitro</span></i><span style="font-family:Verdana;"> antioxidant activity using 1,1-diphenyl 2-picrylhydrazyl (DPPH) assay and EC</span>_{<span style="font-family:Verdana;">50</span>}<span style="font-family:Verdana;"> value was determined. </span><i><span style="font-family:Verdana;">α</span></i><span style="font-family:Verdana;">-Amylase inhibitory and anti-</span><i><span style="font-family:Verdana;">S.</span></i> <i><span style="font-family:Verdana;">aureus</span></i><span style="font-family:Verdana;"> activities were carried out by conventional methods. The mushroom extract showed maximum free radical scavenging activity at a dose of 500 μg/mL with EC</span>_{<span style="font-family:Verdana;">50</span>}<span style="font-family:Verdana;"> value of 22.1399 μg/mL. EC</span>_{<span style="font-family:Verdana;">50</span>}<span style="font-family:Verdana;"> value for the inhibition of </span><i><span style="font-family:Verdana;">α</span></i><span style="font-family:Verdana;">-amylase activity was found 22.6011 μg/mL. </span><i><span style="font-family:Verdana;">G.</span></i> <i><span style="font-family:Verdana;">lucidum</span></i><span styl