Biotyping of Multidrug Resistant <i>Campylobacter jejuni</i>from Poultry and Humans in Northern Region of Ghana

• 作者: Akosua Bonsu Karikari Courage Kosi Setsoafia Saba Stephen Wilson Kpordze
• 来源期刊: 医学微生物学(英文)
• 学科: 数学
• 关键词: Campylobacter Antibiotic Resistance Multidrug Resistance Biotyping Ghana
• 年，卷（期）: 2021,（1）
• 页码范围: 18-31
• 页数: 14页
• 分类号: O17

摘要

<span style="font-family:""><span style="font-family:Verdana;">Thermophilic </span><i><span style="font-family:Verdana;">Campylobacters</span></i><span style="font-family:Verdana;"> are zoonotic bacteria which are universally famous for causing enteritis in humans. They are normally found as commensals in the digestive tract of food animals with poultry being a major re</span><span style="font-family:Verdana;">servoir of the pathogenic species. This study highlighted the presence of</span> <i><span style="font-family:Verdana;">Campylobacter</span></i><span style="font-family:Verdana;"> in poultry (commercial and domestic) and humans (patients and asymptomatic individuals) and characterized strains by biotyping and susceptibility test in the Northern region of Ghana where animal husbandry is commonly practiced but zoonotic studies are limited. A total of 1087 specimens from stools of humans and cloacal swabs of poultry were screened from 25th October, 2017 to 7th May, 2019. Samples were cultured on modified charcoal-cefoperazone-deoxycholate agar and isolates identified using standard microbiological procedures and Lior Biotyping, while the antibiogram of isolates w</span></span><span style="font-family:Verdana;">as</span><span style="font-family:Verdana;"> determined by the Kirby-Bauer disk diffusion method. </span><span style="font-family:Verdana;">The </span><span style="font-family:""><span style="font-family:Verdana;">frequency of </span><i><span style="font-family:Verdana;">Campylobacter</span></i><span style="font-family:Verdana;"> was 43.1% and 12.9% respectively in poultry and humans. </span><i><span style="font-family:Verdana;">Campylobacter jejuni</span></i><span style="font-family:Verdana;"> were recovered from 84% of commercial birds and 64% of domestic birds and in humans significantly </span></span><span style="font-family:Verdana;">fewer</span><span style="font-family:Verdana;"> strains were observed in patients than asymptomatic individuals (p <</span><span style="font-family:""> </span><span styl