Suppression of DRR1 results in the accumulation of insoluble ubiquitinated proteins, which impairs drought stress toleranceFA

• 作者: Seong Gwan Yu Na Hyun Cho Jong Hum Kim Tae Rin Oh Woo Taek Kim
• 来源期刊: 植物学报（英文版）
• 年，卷（期）: 2021,（3）
• 所属期刊栏目: Breakthrough Report
• 页码范围: 431-437
• 页数: 7页
• 语种: 英文

摘要

Drought stress has detrimental effects on plants. Al-though the abscisic acid (ABA)-mediated drought response is well established, defensive mechanisms to cope with dehydration-induced proteotoxicity have been rarely studied. DRR1 was identified as an Arabidopsis drought-induced gene encoding an ER-localized RING-type E3 Ub ligase. Suppression of DRR1 markedly reduced tolerance to drought and proteotoxic stress without altering ABA-mediated germination and stomatal movement. Proteotoxicity-and dehydration-induced insoluble ubiquitinated protein accumulation was more obvious in DRR1 loss-of-function plants than in wild-type plants. These results suggest that DRR1 is involved in an ABA-independent drought stress response possibly through the mitigation of dehydration-induced proteotoxic stress.